Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454428 | 1.00 | PTGS2 (0.36) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6454973 | 0.95 | KDM1A (0.34) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6454975 | 0.95 | KDM1A (0.34) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6454565 | 0.87 | — | — | |
| SCHEMBL6454561 | 0.87 | — | — | |
| SCHEMBL19850824 | 0.84 | PTGS2 (0.41) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6456841 | 0.83 | PTGS2 (0.35) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6456849 | 0.83 | PTGS2 (0.35) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6456844 | 0.83 | PTGS2 (0.35) | PTGS2PTGS1KDM1AMAP1LC3B | |
| SCHEMBL6451969 | 0.81 | L3MBTL1 (0.40) | PTGS2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |