SCHEMBL6454990

SCHEMBL6454990

Cc1ccc(C(=O)c2ccc(-c3ccc(C(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.84
LMNA P02545 3/20 0.84
SRD5A2 P31213 2/20 0.70
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.56
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
HTT P42858 3/20 0.52
PKM P14618 2/20 0.52
ATM Q13315 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HPGD P15428 1/20 0.52
NLRP1 Q9C000 1/20 0.52
GAA P10253 1/20 0.52
NTSR1 P30989 1/20 0.52
RAB9A P51151 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10014118 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL19651362 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL13356677 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL19651365 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL822185 0.92 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL52200 0.92 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL13445258 0.91 LMNA (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL2450704 0.91 ALDH1A1 (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL15496856 0.91 LMNA (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL16622036 0.91 ALDH1A1 (0.70) ALDH1A1LMNASRD5A2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364352-B2 High temperature melt processable semi-crystalline poly(aryl ether ketone) containing a (4-hydroxyphenyl)phthalazin-1(2h)-one comonomer unit POLYMICS, LTD (US) 2019-07-30 US disclosed
EP-2346921-B1 HIGH TEMPERATURE MELT PROCESSABLE SEMI-CRYSTALLINE POLY (ARYL ETHER KETONE) CONTAINING A (4-HYDROXYPHENYL) PHTHALAZIN-1(2H)-ONE COMONOMER UNIT POLYMICS LTD (US) 2019-01-02 EP disclosed
EP-2493981-B1 HIGH TEMPERATURE POLYMER BLENDS OF POLY(ARYL ETHER KETONE PHTHALAZINONE) POLYMICS LTD (US) 2018-06-20 EP disclosed
US-20150252189-A1 HIGH TEMPERATURE POLYMER BLENDS OF POLY(ARYL ETHER KETONE PHTHALAZINONE) POLYMICS LTD (US) 2015-09-10 US disclosed
US-20150252189-A1 HIGH TEMPERATURE POLYMER BLENDS OF POLY(ARYL ETHER KETONE PHTHALAZINONE) POLYMICS LTD (US) 2015-09-10 US disclosed
US-9062163-B2 High temperature polymer blends of poly(aryl ether ketone phthalazinone) POLYMICS, LTD. (US) 2015-06-23 US disclosed
US-9062163-B2 High temperature polymer blends of poly(aryl ether ketone phthalazinone) POLYMICS, LTD. (US) 2015-06-23 US disclosed
EP-2046862-B1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS CA NAT RESEARCH COUNCIL (CA) 2013-02-13 EP disclosed
US-20120147728-A1 HIGH DENSITY DATA STORAGE MEDIUM, METHOD AND DEVICE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-14 US disclosed
US-8169882-B2 High density data storage medium, method and device INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-05-01 US disclosed
US-20100284264-A1 HIGH DENSITY DATA STORAGE MEDIUM, METHOD AND DEVICE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-11-11 US disclosed
WO-2010062361-A1 HIGH TEMPERATURE MELT PROCESSABLE SEMI-CRYSTALLINE POLY (ARYL ETHER KETONE) CONTAINING A (4-HYDROXYPHENYL) PHTHALAZIN-1(2H)-ONE COMONOMER UNIT POLYMICS, LTD (US) 2010-06-03 WO disclosed
US-20100113688-A1 High temperature melt processable semi-crystalline poly (aryl ether ketone) containing a (4-hydroxyphenyl) phthalazin-1 (2H)-one comonomer unit POLYMICS, LTD. 2010-05-06 US disclosed
US-20100113688-A1 High temperature melt processable semi-crystalline poly (aryl ether ketone) containing a (4-hydroxyphenyl) phthalazin-1 (2H)-one comonomer unit POLYMICS, LTD. 2010-05-06 US disclosed
US-20090203806-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-08-13 US disclosed
US-20090203806-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-08-13 US disclosed
US-20080205253-A1 HIGH DENSITY DATA STORAGE MEDIUM, METHOD AND DEVICE GLOBALFOUNDRIES U.S. INC. 2008-08-28 US disclosed
US-20080159114-A1 HIGH DENSITY DATA STORAGE MEDIUM, METHOD AND DEVICE GLOBALFOUNDRIES INC. (KY) 2008-07-03 US disclosed
WO-2008009102-A1 POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-01-24 WO disclosed
WO-2007128137-A1 POLY(ARYLENE ETHER)S WITH GRAFTING CAPABILITY FROM A BISPHENOL OR BISTHIOPHENOL MONOMER NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-11-15 WO disclosed