SCHEMBL13356677

SCHEMBL13356677

Cc1ccc(C(=O)c2ccc(-c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.84
▸ LMNA P02545 3/20 0.84
▸ SRD5A2 P31213 2/20 0.70
▸ CES2 O00748 2/20 0.59
▸ CES1 P23141 2/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ CNR1 P21554 1/20 0.53
▸ CNR2 P34972 1/20 0.53
▸ HTT P42858 3/20 0.52
▸ PKM P14618 2/20 0.52
▸ ATM Q13315 2/20 0.52
▸ NPSR1 Q6W5P4 2/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ HPGD P15428 1/20 0.52
▸ NLRP1 Q9C000 1/20 0.52
▸ GAA P10253 1/20 0.52
▸ NTSR1 P30989 1/20 0.52
▸ RAB9A P51151 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19651365 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL6454990 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL10014118 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL19651362 1.00 ALDH1A1 (0.84) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL822185 0.92 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL52200 0.92 ALDH1A1 (1.00) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL13445258 0.91 LMNA (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL15496856 0.91 LMNA (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL2450704 0.91 ALDH1A1 (0.70) ALDH1A1LMNASRD5A2CES2CES1
SCHEMBL16622036 0.91 ALDH1A1 (0.70) ALDH1A1LMNASRD5A2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134844-A1 Block Copolymer, Ion-Exchange Membrane And Method Of Preparing Block Copolymer KOREA INSTITUTE OF ENERGY RESEARCH (KR) 2018-05-17 — — US disclosed
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-11-30 — — US disclosed
EP-2184327-B1 Azo pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2013-05-15 — — EP disclosed
US-8309696-B2 AZO pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2012-11-13 — — US disclosed
US-8309696-B2 AZO pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2012-11-13 — — US disclosed
US-7910180-B2 Liquid crystal and liquid crystal display TOKYO INSTITUTE OF TECHNOLOGY (JP) 2011-03-22 — — US disclosed
US-20100155663-A1 Liquid Crystal and Liquid Crystal Display TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-06-24 — — US disclosed
EP-2184327-A2 Azo pigment, electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2010-05-12 — — EP disclosed
US-20100075239-A1 AZO PIGMENT, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-03-25 — — US disclosed
US-20100075239-A1 AZO PIGMENT, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-03-25 — — US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 — — US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075239-A1 AZO PIGMENT, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CRY1, IK, APC ALDH1A1 729/4885LMNA 3290/4885SRD5A2 985/4885
US-20170342324-A1 BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA MTX1, S100A11, MCRS1 ALDH1A1 3730/4885LMNA 2247/4885SRD5A2 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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