⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776798 | 0.90 | — | — | |
| SCHEMBL28776768 | 0.87 | — | — | |
| SCHEMBL28776780 | 0.85 | — | — | |
| SCHEMBL5360795 | 0.76 | USP2 (0.41) | — | |
| SCHEMBL28722251 | 0.75 | BTK (0.31) | — | |
| SCHEMBL7978037 | 0.73 | BTK (0.30) | — | |
| SCHEMBL8880684 | 0.73 | RBP4 (0.33) | — | |
| SCHEMBL4004639 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL28588874 | 0.71 | RBP4 (0.33) | — | |
| SCHEMBL4829842 | 0.70 | NPSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20050256107-A1 | New substituted thiophene carboxamides, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| US-6713580-B2 | CYCLIZED AMINO ACIDS ARE COUPLED TO A POLYSTYRENE DERIVATIVE FOR USE IN SYNTHESIS OF PEPTIDES AND OF AMINO ACID CONTAINING COMPOUNDS FOR DRUG DISCOVERY | PHARMACORE, INC. | 2004-03-30 | — | — | US | disclosed |
| EP-1373195-A2 | QUATERNARY AMINO ACIDS ON SOLID SUPPORTS | PharmaCore, Inc, (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020086949-A1 | Cyclized amino acids are coupled to a polystyrene derivative for use in synthesis of peptides and of amino acid containing compounds for drug discovery | PHARMACORE, INC. | 2002-07-04 | — | — | US | disclosed |
| WO-2002046128-A2 | QUATERNARY AMINO ACIDS ON SOLID SUPPORTS | PHARMACORE, INC. (US) | 2002-06-13 | — | — | WO | disclosed |