SCHEMBL7978037

SCHEMBL7978037

CC(C)(C)OC(=O)C1(C(=O)O)CCC(N)CC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
GRM2 Q14416 2/20 0.30
GRM3 Q14832 2/20 0.30
GRM4 Q14833 2/20 0.30
CYP1A2 P05177 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
LMNA P02545 1/20 0.30
GRM5 P41594 1/20 0.30
MTOR P42345 1/20 0.30
GRM1 Q13255 1/20 0.30
PLCB1 Q9NQ66 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8880684 0.83 RBP4 (0.33)
SCHEMBL7972576 0.82 PLG (0.37) LMNA
Ammonia Solution, Strong SCHEMBL28588874 0.81 RBP4 (0.33)
SCHEMBL28722251 0.81 BTK (0.31) BTKGRM2GRM3GRM4CYP1A2
SCHEMBL4742520 0.80 CYP4F2 (0.31) BTK
SCHEMBL4829842 0.80 NPSR1 (0.31) BTK
SCHEMBL28240411 0.79 CHRM2 (0.32) CHRM2CHRM1CHRM3
SCHEMBL2306586 0.79 MAPK1 (0.33) CHRM2CHRM1CHRM3GRM2GRM3
SCHEMBL2306584 0.79 MAPK1 (0.33) CHRM2CHRM1CHRM3GRM2GRM3
SCHEMBL23293553 0.78 CYP2C19 (0.32) BTKCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423075-B1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2026-03-25 EP disclosed
US-20250011313-A1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2025-01-09 US disclosed
EP-4423075-A1 CCR6 RECEPTOR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2024-09-04 EP disclosed
WO-2023102140-A1 TMPRSS2 INHIBITORS AND METHODS OF USE TOPSPIN THERAPEUTICS, INC. (US) 2023-06-08 WO disclosed
WO-2023073082-A1 CCR6 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2023-05-04 WO disclosed
CN-114213435-B Preparation and application of bis- (10-deoxydihydroartemisinin) -phloroglucinol derivative 云白药征武科技(上海)有限公司 2023-03-21 CN disclosed
CN-114213435-A Preparation and application of bis- (10-deoxydihydroartemisinin) -phloroglucinol derivative 云白药征武科技(上海)有限公司 2022-03-22 CN disclosed
WO-2001054507-A1 METHODS FOR KILLING NEMATODES AND NEMATODE EGGS USING OXADIAZOLE AND OXAIMIDAZOLE COMPOUNDS AKKADIX CORPORATION (US) 2001-08-02 WO disclosed
WO-2001054508-A1 MATERIALS AND METHODS FOR KILLING NEMATODES AND NEMATODE EGGS AKKADIX CORPORATION (US) 2001-08-02 WO disclosed
WO-2001002375-A1 PROCESS FOR SYNTHESIZING OXADIAZOLES CHEMRX ADVANCED TECHNOLOGIES, INC. (US) 2001-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011313-A1 CCR6 RECEPTOR MODULATORS CCR6, CCR1, CCR4 BTK 1611/4885CHRM2 756/4885CHRM1 1040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.