SCHEMBL8880684

SCHEMBL8880684

CC(C)(C)OC(=O)C1(C(=O)O)CC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 2/20 0.33
FFAR3 O14843 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
DGAT1 O75907 1/20 0.32
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28588874 0.98 RBP4 (0.33) RBP4FFAR3CYP4F2CYP4A11DGAT1
SCHEMBL4742520 0.91 CYP4F2 (0.31) FFAR3CYP4F2CYP4A11DGAT1
SCHEMBL4829842 0.91 NPSR1 (0.31) FFAR3CYP4F2CYP4A11DGAT1
SCHEMBL23293553 0.90 CYP2C19 (0.32) FFAR3CYP4F2CYP4A11
SCHEMBL7884001 0.88 CYP2C19 (0.31) CYP4F2CYP4A11
SCHEMBL2146137 0.88 OPRM1 (0.34) CYP4F2CYP4A11
SCHEMBL5360795 0.86 USP2 (0.41) USP2SMN1; SMN2
SCHEMBL7978037 0.83 BTK (0.30)
SCHEMBL80613 0.82 DGAT1 (0.37) CYP4F2CYP4A11DGAT1USP2SMN1; SMN2
SCHEMBL1087991 0.81 MAPK1 (0.31) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178154-B Preparation method of fullerene ester derivative 湖北大学 2025-04-11 CN disclosed
EP-4440700-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-09 EP disclosed
CN-118355020-A Therapeutic compounds for HIV virus infection 吉利德科学公司 2024-07-16 CN disclosed
WO-2023102529-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed
US-11661403-B2 Oxadiazole compounds VIVACE THERAPEUTICS, INC. (US) 2023-05-30 US disclosed
US-11661403-B2 Oxadiazole compounds VIVACE THERAPEUTICS, INC. (US) 2023-05-30 US disclosed
US-11357755-B2 Compounds for controlling arthropods BAYER ANIMAL HEALTH GMBH (DE) 2022-06-14 US disclosed
EP-4003963-A1 PYRAZOLE DERIVATIVES FOR CONTROLLING ARTHROPODS Bayer Animal Health GmbH (DE) 2022-06-01 EP disclosed
CN-114423740-A Pyrazole derivatives for controlling arthropods 拜耳动物保健有限责任公司 2022-04-29 CN disclosed
US-11247992-B2 Cyclopropylamines as LSD1 inhibitors INCYTE CORPORATION (US) 2022-02-15 US disclosed
US-20150225401-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS INCYTE CORPORATION (US) 2015-08-13 US disclosed
US-8729095-B2 3-(biaryloxy)propionic acid derivatives for prevention and/or treatment of thromboembolic diseases DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-05-20 US disclosed
US-20120245152-A1 3-(BIARYOXY)PROPIONIC ACID DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-09-27 US disclosed
EP-2471792-A1 3-(BIARYLOXY) PROPIONIC ACID DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2012-07-04 EP disclosed
US-5605925-A COGNITION ACTIVATOR; ALZHEIMER'S DISEASE HOECHST MARION ROUSSEL, INC. (US) 1997-02-25 US disclosed
US-5580987-A TREATING 1-PHTHALIMIDOPYRROLE WITH BASE TO YIELD 1-AMINOPYRROLE, REACTING WITH SUBSTITUTED AMINO ACID TO OBTAIN DESIRED COMPOUND HOECHST MARION ROUSSEL, INC. (US) 1996-12-03 US disclosed
US-5576446-A GLYCINE PARTIAL AGONIST AND ENHANCEMENT OF LEARNING AND MEMORY, TREATMENT OF ALZHEIMER'S HOECHST MARION ROUSSEL, INC. (US) 1996-11-19 US disclosed
US-5428053-A Treats alzheimer's disease and other senile dementias HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1995-06-27 US disclosed
EP-0582182-A1 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1994-02-09 EP disclosed
US-5274116-A 1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1993-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225401-A1 CYCLOPROPYLAMINES AS LSD1 INHIBITORS KDM1B, KDM1A, KDM2A RBP4 4480/4885FFAR3 3006/4885CYP4F2 1640/4885
US-20120245152-A1 3-(BIARYOXY)PROPIONIC ACID DERIVATIVE F11, PF4, F2 RBP4 816/4885FFAR3 21/4885CYP4F2 2229/4885
US-11247992-B2 Cyclopropylamines as LSD1 inhibitors KDM1B, KDM1A, KDM2A RBP4 4480/4885FFAR3 3006/4885CYP4F2 1640/4885
US-11357755-B2 Compounds for controlling arthropods DDT, AAAS, AGO2 RBP4 566/4885FFAR3 2701/4885CYP4F2 19/4885
US-11661403-B2 Oxadiazole compounds YAP1, TEAD2, TEAD3 RBP4 3608/4885FFAR3 4209/4885CYP4F2 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.