Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306203 | 0.93 | CES2 (0.44) | ALDH1A1PTGS2CES2CES1OPRM1 | |
| SCHEMBL4880653 | 0.93 | CES2 (0.44) | ALDH1A1PTGS2CES2CES1OPRM1 | |
| SCHEMBL11119491 | 0.93 | CES2 (0.44) | ALDH1A1PTGS2CES2CES1OPRM1 | |
| SCHEMBL27614814 | 0.83 | CES2 (0.51) | POLBALDH1A1KDM4ECES2CES1 | |
| SCHEMBL11655496 | 0.82 | LMNA (0.57) | POLBALDH1A1CES2CES1LMNA | |
| SCHEMBL11536491 | 0.82 | POLB (0.42) | POLBALDH1A1KDM4EPTGS2CES2 | |
| SCHEMBL1508070 | 0.81 | POLB (0.54) | POLBALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL399241 | 0.81 | POLB (0.46) | POLBALDH1A1KDM4EPTGS2LMNA | |
| SCHEMBL4875739 | 0.80 | LMNA (0.53) | POLBALDH1A1LMNAHSD17B10 | |
| SCHEMBL6198748 | 0.80 | POLB (0.43) | POLBALDH1A1KDM4ELMNAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900280-B2 | Acid macromonomers and their method of preparation | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040072978-A1 | Compositions of acid macromonomers and their method of preparation | CIBA SPECIALTY CHEMICALS CORP. | 2004-04-15 | — | — | US | disclosed |
| EP-1392736-A2 | ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION | Ciba SC Holding AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1056790-B1 | METHOD FOR RETARDED ANIONIC POLYMERIZATION | BASF AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002079271-A2 | ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |
| EP-0624157-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM -g(g),-g(d)-EPOXYBUTENES. | EASTMAN CHEM CO (US) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993010111-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM η,δ-EPOXYBUTENES | EASTMAN KODAK COMPANY (US) | 1993-05-27 | — | — | WO | disclosed |