Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306203 | 1.00 | CES2 (0.44) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL11119491 | 1.00 | CES2 (0.44) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL6455814 | 0.93 | POLB (0.44) | CES2CES1ALDH1A1OPRM1OPRD1 | |
| SCHEMBL22471826 | 0.82 | NAAA (0.51) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL11058895 | 0.82 | CSNK1E (0.45) | CSNK1ENAAAASAH1ALDH1A1ACER2 | |
| SCHEMBL22471814 | 0.82 | NAAA (0.51) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL28256178 | 0.82 | NAAA (0.51) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL22471868 | 0.82 | NAAA (0.51) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL22471835 | 0.82 | NAAA (0.51) | CES2CES1CSNK1ENAAAASAH1 | |
| SCHEMBL27583368 | 0.82 | PTGS2 (0.44) | CES2CES1CSNK1ENAAAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080107905-A1 | crosslinked rubber layer containing a copolymer of acrylonitrile, butadiene modified with monobutyl maleate or itaconate, a modified polyethyl acrylate or copolymer with acrylonitrile, a hexamethylenediamine carbamate crosslinker, a phosphonium benzotriazole salt, a fluoropolymer; oil, ozone resistance | ZEON CORPORATION (JP) | 2008-05-08 | — | — | US | disclosed |
| EP-1795341-A1 | LAYERED RUBBER PRODUCT | ZEON CORPORATION (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6037062-A | Layered molding | TOYODA GOSEI CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| US-5798158-A | LAYERED FLUORINE-CONTAINING COPOLYMER OR TERPOLYMER, EPICHLOROHYDRIN RUBBER CONTAINING ORGANIC PHOSPHONIUM COMPOUND CROSSLINKED AT INTERFACE | TOYODA GOSEI CO., LTD. (JP) | 1998-08-25 | — | — | US | disclosed |