Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456231 | 1.00 | DGAT1 (0.33) | DGAT1SOAT1ALDH1A1CYP2C9TRPV3 | |
| SCHEMBL6454930 | 0.91 | CYP2C9 (0.39) | DGAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL6454926 | 0.91 | CYP2C9 (0.39) | DGAT1SOAT1ALDH1A1CYP2C9 | |
| SCHEMBL6453734 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453731 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452787 | 0.89 | ESR2 (0.33) | ALDH1A1CYP2C9 | |
| SCHEMBL6452793 | 0.89 | ESR2 (0.33) | ALDH1A1CYP2C9 | |
| SCHEMBL6457720 | 0.88 | KIF11 (0.42) | — | |
| SCHEMBL6457723 | 0.88 | KIF11 (0.42) | — | |
| SCHEMBL6462251 | 0.88 | MAPT (0.33) | ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |