Dimethenamid

Dimethenamid

SCHEMBL6456746

CC(C)c1nn(C(=O)NC(C)(C)C)c(=O)n1N.COC[C@H](C)N(C(=O)CCl)c1c(C)csc1C

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolachor SCHEMBL2814388 0.84 ALDH1A1 (0.45) THRB
Dimethenamid SCHEMBL5087814 0.78 THRB (1.00) THRB
Dimethenamid SCHEMBL53864 0.78 THRB (1.00) THRB
Dimethenamid SCHEMBL18223 0.78 THRB (1.00) THRB
Dimethachlor SCHEMBL2814025 0.77 TP53 (0.33) THRB
Dimethenamid SCHEMBL20723471 0.77 THRB (0.97) THRB
Dimethenamid SCHEMBL20723446 0.77 THRB (0.97) THRB
Metolachor SCHEMBL7059772 0.77 ALDH1A1 (0.39) THRB
Propachlor SCHEMBL2813734 0.74 ALDH1A1 (0.51)
Metolachor SCHEMBL7057714 0.74 MEN1 (0.38) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed
US-20050043181-A1 Carbamoyl triazolinone-based herbicides FEUCHT DIETER (DE) 2005-02-24 US disclosed
US-6821926-B1 SYNERGISTIC ACTIVE COMPOUND COMBINATIONS WITH BUTAFENACIL-ALLYL BAYER AKTIENGESELLSCHAFT (DE) 2004-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043181-A1 Carbamoyl triazolinone-based herbicides DDT, GATD3, AADAC THRB 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.