Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456844 | 1.00 | PTGS2 (0.35) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL6456849 | 1.00 | PTGS2 (0.35) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL6462612 | 0.96 | MAP1LC3B (0.33) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL6462613 | 0.96 | MAP1LC3B (0.33) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL7918486 | 0.96 | MAP1LC3B (0.33) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL6462607 | 0.96 | MAP1LC3B (0.33) | PTGS2PTGS1MAP1LC3BSLC6A3SLC6A4 | |
| SCHEMBL5684210 | 0.89 | SLC6A3 (0.33) | MAP1LC3BSLC6A3SLC6A4SLC6A2KDM1A | |
| SCHEMBL5684207 | 0.89 | SLC6A3 (0.33) | MAP1LC3BSLC6A3SLC6A4SLC6A2KDM1A | |
| SCHEMBL6452715 | 0.88 | SLC6A2 (0.31) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6452722 | 0.88 | SLC6A2 (0.31) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |