Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 14/20 | 0.60 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.48 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044251 | 0.86 | HCAR3 (0.53) | HCAR3HPGDHCAR2EHMT2 | |
| SCHEMBL6044721 | 0.86 | HCAR3 (0.66) | HCAR3 | |
| SCHEMBL6044303 | 0.75 | HCAR3 (1.00) | HCAR3HPGDHCAR2 | |
| SCHEMBL5318327 | 0.72 | HDAC6 (0.81) | EHMT2EHMT1HDAC6 | |
| SCHEMBL5828225 | 0.70 | HCAR3 (0.60) | HCAR3HPGDHCAR2 | |
| SCHEMBL18033708 | 0.70 | HCAR3 (0.60) | HCAR3HPGDHCAR2 | |
| SCHEMBL2490016 | 0.70 | HCAR3 (0.60) | HCAR3HPGDHCAR2 | |
| SCHEMBL5921944 | 0.69 | HCAR3 (0.68) | HCAR3HPGDHCAR2 | |
| SCHEMBL30138440 | 0.68 | HTT (0.62) | HCAR3HPGDEHMT2EHMT1 | |
| SCHEMBL8424378 | 0.68 | HCAR3 (0.66) | HCAR3HPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585541-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056347-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |