Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457624 | 1.00 | IDO1 (0.33) | IDO1DRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6459949 | 0.91 | OPRM1 (0.35) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6459954 | 0.91 | OPRM1 (0.35) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6451465 | 0.89 | DRD2 (0.33) | IDO1DRD2 | |
| SCHEMBL6451469 | 0.89 | DRD2 (0.33) | IDO1DRD2 | |
| SCHEMBL6453031 | 0.89 | DRD2 (0.32) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6453036 | 0.89 | DRD2 (0.32) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6458923 | 0.88 | GAA (0.33) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6458915 | 0.88 | GAA (0.33) | IDO1DRD2CNR1CNR2 | |
| SCHEMBL6455896 | 0.88 | GAA (0.33) | IDO1DRD2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |