Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027954 | 0.89 | MAOB (0.56) | NISCHMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL5033131 | 0.78 | PRMT1 (0.62) | NISCHMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL26125464 | 0.76 | NISCH (0.67) | NISCHMAOBKDM4E | |
| SCHEMBL5030461 | 0.75 | PRMT1 (0.64) | NISCHMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL8196401 | 0.75 | NISCH (0.74) | NISCHMAOBMAOAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8202584 | 0.75 | MAOB (0.41) | NISCHMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL8187860 | 0.75 | ADRA2A (0.48) | NISCHKDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL8199611 | 0.74 | NISCH (0.63) | NISCHMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL9189709 | 0.73 | NISCH (0.85) | NISCHMAOB | |
| SCHEMBL8200480 | 0.73 | NISCH (0.44) | NISCHMAOBMAOAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | NISCH 501/4885MAOB 2348/4885MAOA 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.