Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458212 | 1.00 | PTGS2 (0.38) | PTGS2PTGS1CSNK1A1CSNK1DRPS6KA3 | |
| SCHEMBL6459690 | 0.90 | CNR1 (0.31) | — | |
| SCHEMBL6459684 | 0.90 | CNR1 (0.31) | — | |
| SCHEMBL6463255 | 0.88 | NOTUM (0.32) | PTGS2 | |
| SCHEMBL6463251 | 0.88 | NOTUM (0.32) | PTGS2 | |
| SCHEMBL6455766 | 0.87 | — | — | |
| SCHEMBL6455760 | 0.87 | — | — | |
| SCHEMBL18392539 | 0.87 | CSNK1A1 (0.40) | PTGS2PTGS1CSNK1A1CSNK1DRPS6KA3 | |
| SCHEMBL6458589 | 0.87 | SIGMAR1 (0.37) | MAPK11MAPK14 | |
| SCHEMBL6459540 | 0.87 | MEN1 (0.33) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |