Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459535 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHRL3MBTL1TRPV1 | |
| SCHEMBL6458205 | 0.87 | PTGS2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6458212 | 0.87 | PTGS2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452628 | 0.87 | CHEK1 (0.36) | L3MBTL1TRPV1GRIN2B | |
| SCHEMBL6452622 | 0.87 | CHEK1 (0.36) | L3MBTL1TRPV1GRIN2B | |
| SCHEMBL6458931 | 0.87 | MAT2A (0.35) | CHRNB2CHRNA4MAT2A | |
| SCHEMBL6458937 | 0.87 | MAT2A (0.35) | CHRNB2CHRNA4MAT2A | |
| SCHEMBL6464722 | 0.86 | KDM1A (0.43) | MEN1KMT2AL3MBTL1KDM1A | |
| SCHEMBL6464726 | 0.86 | KDM1A (0.43) | MEN1KMT2AL3MBTL1KDM1A | |
| SCHEMBL6459690 | 0.86 | CNR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |