Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450369 | 0.78 | MYC (0.32) | TRPA1ATMP2RX7TSHRSMN1; SMN2 | |
| SCHEMBL19838629 | 0.78 | TRPA1 (0.48) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| SCHEMBL5147351 | 0.78 | TRPA1 (0.37) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| SCHEMBL30834716 | 0.78 | TRPA1 (0.52) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| SCHEMBL218508 | 0.78 | TRPA1 (0.52) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| SCHEMBL1422076 | 0.76 | HTR7 (0.31) | NUDT1 | |
| Hydrogen Sulfide SCHEMBL1538405 | 0.75 | TRPA1 (0.50) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL22444763 | 0.75 | TRPA1 (0.50) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL15862222 | 0.75 | TRPA1 (0.50) | TRPA1ATMNUDT1P2RX7CYP1A2 | |
| SCHEMBL9412187 | 0.71 | PDCD1 (0.38) | CYP2A6SMN1; SMN2CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119779-B2 | Phosphoramidate derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED | 2012-02-21 | — | — | US | disclosed |
| US-20070275910-A1 | Phosphoramidate Derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2007-11-29 | — | — | US | disclosed |
| EP-1622966-A1 | POLYMER NETWORKS | The University of Reading (GB) | 2006-02-08 | — | — | EP | disclosed |
| US-6822118-B1 | CATALYTIC REACTION USING IRIDIUM COMPOUND UNDER HIGH PRESSURE IN PRESENCE OF METAL- OR AMMONIUM- CHLORIDE, BROMIDE, OR IODIDE AND ACID | SYNGENTA CROP PROTECTION, INC. | 2004-11-23 | — | — | US | disclosed |
| WO-2004094504-A1 | POLYMER NETWORKS | THE UNIVERSITY OF READING (GB) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275910-A1 | Phosphoramidate Derivatives | HRH4, HRH3, NR1H4 | TRPA1 1881/4885ATM 3658/4885NUDT1 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.