SCHEMBL645857

SCHEMBL645857

CC(C)OC(=O)COCCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 4/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
CYP2D6 P10635 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401325 0.96 MEN1 (0.44) TDP1LMNAMAPTTSHRMAPK1
SCHEMBL1401407 0.96 MEN1 (0.44) TDP1LMNAMAPTTSHRMAPK1
SCHEMBL7651937 0.86 TDP1 (0.43) TDP1LMNAMAPTTSHRALDH1A1
SCHEMBL11115364 0.84 LMNA (0.46) TDP1LMNAMAPTTSHRALDH1A1
SCHEMBL26419587 0.83 LMNA (0.48) TDP1LMNAMAPTTSHRALDH1A1
SCHEMBL5606265 0.83 LMNA (0.48) TDP1LMNAMAPTTSHRALDH1A1
SCHEMBL5085700 0.82 LMNA (0.42) TDP1LMNAMAPTTSHRMAPK1
SCHEMBL23754412 0.82 CYP19A1 (0.40) TDP1TSHRMAPK1ALDH1A1MEN1
SCHEMBL21373956 0.82 ALDH1A1 (0.38) TDP1MAPTTSHRMAPK1ALDH1A1
SCHEMBL12588874 0.81 TSHR (0.43) TDP1LMNAMAPTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114930251-A Copolymer, anticorrosive coating composition containing the copolymer, dispersant containing the copolymer, and resist resin containing the copolymer 日油株式会社 2022-08-19 CN disclosed
WO-2021153545-A1 COPOLYMER, RUST PREVENTIVE COATING COMPOSITION CONTAINING SAME, DISPERSANT AND RESIST RESIN 日油株式会社 2021-08-05 WO disclosed
CN-105860054-B Non-aqueous dispersant and non-aqueous dispersion composition 日油株式会社 2020-10-09 CN disclosed
US-10793666-B2 Polyisocyanate composition, polyurethane resin and two-component curable polyurethane composition MITSUI CHEMICALS, INC. (JP) 2020-10-06 US disclosed
US-20200179428-A1 CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES MERCK SHARP & DOHME CORP. (US) 2020-06-11 US disclosed
EP-3309185-B1 POLYISOCYANATE COMPOSITION, POLYURETHANE RESIN AND TWO-COMPONENT CURABLE POLYURETHANE COMPOSITION MITSUI CHEMICALS INC (JP) 2020-01-29 EP disclosed
US-20180155486-A1 POLYISOCYANATE COMPOSITION, POLYURETHANE RESIN AND TWO-COMPONENT CURABLE POLYURETHANE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2018-06-07 US disclosed
EP-3309185-A1 POLYISOCYANATE COMPOSITION, POLYURETHANE RESIN, AND TWO-COMPONENT CURABLE POLYURETHANE COMPOSITION Mitsui Chemicals, Inc. (JP) 2018-04-18 EP disclosed
US-8632937-B2 UV-sensitive lithographic printing plate precursor with benzoxazole derivative and analogues thereof as sensitizer EASTMAN KODAK COMPANY (US) 2014-01-21 US disclosed
US-8119331-B2 Photopolymer composition usable for lithographic plates KODAK GRAPHIC COMMUNICATIONS GMBH (DE) 2012-02-21 US disclosed
WO-2006087102-A2 PROCESS FOR THE PRODUCTION OF LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-08-24 WO disclosed
US-20060154169-A1 Radiation-sensitive compositions comprising a 1,4-dihydropyridine sensitizer and imageable elements based thereon KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-07-13 US disclosed
WO-2006053689-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS WITH OLIGOMERIC OR POLYMERIC SENSITIZERS KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-05-26 WO disclosed
WO-2006008073-A2 LITHOGRAPHIC PRINTING PLATES WITH HIGH PRINT RUN STABILITY KODAK POLYCHROME GRAPHICS GMBH (DE) 2006-01-26 WO disclosed
US-20050153221-A1 Dummy plate precursor for planographic printing and method for producing printed plate and dummy plate FUJI PHOTO FILM CO., LTD. 2005-07-14 US disclosed
EP-1552954-A2 Dummy plate precursor for planographic printing and method for producing printed plate and dummy plate Fuji Photo Film Co., Ltd. (JP) 2005-07-13 EP disclosed
WO-2004111731-A1 RADIATION-SENSITIVE COMPOSITIONS COMPRISING A 1,4-DIHYDROPYRIDINE SENSITIZER AND IMAGEABLE ELEMENTS BASED THEREON KODAK POLYCHROME GRAPHICS GMBH (DE) 2004-12-23 WO disclosed
US-6670096-B2 Support with a hydrophilic organic polymer compound chemically bonded to a surface, and an ionic compound bonded to the organic polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-12-30 US disclosed
US-20020106583-A1 Support with a hydrophilic organic polymer compound chemically bonded to a surface, and an ionic compound bonded to the organic polymer FUJIFILM CORPORATION (JP) 2002-08-08 US disclosed
EP-1211096-A1 Base material for lithographic printing plate and lithographic printing plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200179428-A1 CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES PNP, TYMP, ENTPD5 TDP1 961/4885LMNA 2555/4885MAPT 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.