Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26315999 | 0.91 | TSHR (0.44) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL5085700 | 0.87 | LMNA (0.42) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL5607572 | 0.87 | LMNA (0.47) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL7651937 | 0.87 | TDP1 (0.43) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL24033557 | 0.87 | TSHR (0.41) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL28285838 | 0.87 | MAPT (0.41) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL11912087 | 0.85 | MAPT (0.43) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL11051208 | 0.85 | LMNA (0.37) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL15148212 | 0.85 | LMNA (0.37) | LMNATSHRMAPTTDP1CYP2D6 | |
| SCHEMBL5606265 | 0.84 | LMNA (0.48) | LMNATSHRMAPTTDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| EP-0111997-A2 | Vinyl carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | LMNA 248/4885TSHR 2733/4885MAPT 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.