Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458589 | 1.00 | SIGMAR1 (0.37) | SIGMAR1HTR2CP2RY14CHRNB2CHRNA4 | |
| SCHEMBL18392462 | 0.88 | HTR2C (0.41) | SIGMAR1HTR2CP2RY14CHRNB2CHRNA4 | |
| SCHEMBL6458205 | 0.87 | PTGS2 (0.38) | MAPK11MAPK14 | |
| SCHEMBL6458212 | 0.87 | PTGS2 (0.38) | MAPK11MAPK14 | |
| SCHEMBL6459684 | 0.86 | CNR1 (0.31) | CNR1 | |
| SCHEMBL6459690 | 0.86 | CNR1 (0.31) | CNR1 | |
| SCHEMBL6455885 | 0.85 | APP (0.41) | SIGMAR1HTR2CP2RY14CHRNB2CHRNA4 | |
| SCHEMBL6455881 | 0.85 | APP (0.41) | SIGMAR1HTR2CP2RY14CHRNB2CHRNA4 | |
| SCHEMBL6452622 | 0.84 | CHEK1 (0.36) | RPS6KB1 | |
| SCHEMBL6452645 | 0.84 | SIGMAR1 (0.35) | SIGMAR1HTR2CP2RY14CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |