Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28093520 | 0.98 | NCF1 (0.47) | NCF1NOS2BACE1NPC1RAB9A | |
| Imidazole SCHEMBL3822257 | 0.83 | ALDH1A1 (0.37) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL329691 | 0.81 | CYP1A2 (0.50) | NCF1NOS2BACE1LMNACA12 | |
| SCHEMBL11679239 | 0.81 | NCF1 (0.45) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL156070 | 0.79 | ALDH1A1 (0.48) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL5609339 | 0.79 | NCF1 (0.43) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL4011347 | 0.79 | PTGS2 (0.49) | NCF1NOS2BACE1LMNACA12 | |
| SCHEMBL14194322 | 0.79 | NCF1 (0.43) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL546320 | 0.79 | MGAM (0.47) | NCF1NOS2BACE1NPC1RAB9A | |
| SCHEMBL11679882 | 0.79 | ALDH1A1 (0.46) | NCF1NOS2BACE1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118439998-A | Preparation and application of quinoline thioglycollic acid sulfonamide derivative | 江苏正大清江制药有限公司 | 2024-08-06 | — | — | CN | claimed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | claimed |
| CN-101141890-A | Cooling compounds | GIVAUDAN SA (CH) | 2008-03-12 | — | — | CN | claimed |
| EP-1860960-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2007-12-05 | — | — | EP | claimed |
| CN-1844119-A | Near infrared fluorescent probe for detecting zinc ion in cell and its synthesis method and use | UNIV SHANDONG NORMAL (CN) | 2006-10-11 | — | — | CN | claimed |
| WO-2006099762-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-09-28 | — | — | WO | claimed |
| US-5977169-A | FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES | PHARMACIA & UPJOHN COMPANY | 1999-11-02 | — | — | US | claimed |
| EP-0720607-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1996-07-10 | — | — | EP | claimed |
| WO-1995007901-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1995-03-23 | — | — | WO | claimed |
| EP-0602427-A1 | Substituted quinolinylsulphonylureas | BAYER AG (DE) | 1994-06-22 | — | — | EP | claimed |
| EP-0051465-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | claimed |
| CN-121818673-A | Application of quinoline sulfonamide compound | 昆明医科大学 | 2026-04-10 | — | — | CN | disclosed |
| CN-121818673-A | Application of quinoline sulfonamide compound | 昆明医科大学 | 2026-04-10 | — | — | CN | disclosed |
| CN-121735932-A | Oxazoline derived tridentate N, N, N-ligand and synthesis method and application thereof | 南方科技大学 | 2026-03-27 | — | — | CN | disclosed |
| EP-3728194-B1 | QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | OTAGO INNOVATION LTD (NZ) | 2025-06-04 | — | — | EP | disclosed |
| EP-0051465-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-16 | — | — | EP | disclosed |
| US-4453970-A | Herbicidal triazinyl sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4369320-A | PLANT GROWTH RETARDERS, HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0051465-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| EP-0051465-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | NCF1 218/4885NOS2 2677/4885BACE1 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.