Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.61 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27419680 | 0.92 | OPRM1 (0.63) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL6459794 | 0.91 | OPRD1 (0.77) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL28269801 | 0.89 | OPRM1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Quinoline SCHEMBL27847357 | 0.88 | OPRM1 (0.63) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Quinoline SCHEMBL27736709 | 0.88 | OPRD1 (0.65) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL27702598 | 0.88 | OPRD1 (0.65) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082084 | 0.87 | OPRD1 (0.76) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL27816812 | 0.87 | OPRM1 (0.64) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL27496008 | 0.87 | OPRD1 (0.66) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082085 | 0.86 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102584668-A | Method for preparing 2,3-dibromo-5-benzoyl pyrrole | SYNCHEM BENGBU TECHNOLOLY CO LTD | 2012-07-18 | — | — | CN | disclosed |