Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.66 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicomorphine SCHEMBL680036 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Nicomorphine SCHEMBL29349768 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Nicomorphine SCHEMBL26237 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Nicomorphine SCHEMBL29408441 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL15501040 | 0.90 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL6459794 | 0.90 | OPRD1 (0.77) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082085 | 0.90 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Nicomorphine SCHEMBL395672 | 0.90 | OPRD1 (0.68) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Nicomorphine SCHEMBL1649977 | 0.90 | OPRD1 (0.68) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL12082084 | 0.89 | OPRD1 (0.76) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058608-A | Pentazocine prodrug for long-acting injection, preparation method and application | 安徽益普克医药科技发展有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-111447927-A | Naloxone transdermal drug delivery device and method of use thereof | 帝国制药美国公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-110831575-A | Pharmaceutical preparation | 卡里亚制药控股有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110658337-A | Diagnosis and treatment of autoimmune diseases | 戴埃克斯有限公司 | 2020-01-07 | — | — | CN | disclosed |
| CN-110612103-A | Pharmaceutical composition comprising meloxicam | 艾克萨姆治疗公司 | 2019-12-24 | — | — | CN | disclosed |
| CN-100393713-C | Therapeutic agents useful for treating pain | EURO CELTIQUE SA (LU) | 2008-06-11 | — | — | CN | disclosed |
| CN-1190438-C | Nabufulin polybasic ester derivative and its production method | HU YOUPU (CN) | 2005-02-23 | — | — | CN | disclosed |
| CN-1354740-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-06-19 | — | — | CN | disclosed |
| CN-1321643-A | Nabufulin polybasic ester derivative and its production method | HU YOUPU (CN) | 2001-11-14 | — | — | CN | disclosed |