SCHEMBL6460105

SCHEMBL6460105

CNS(=O)(=O)CCc1ccc(CC(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
PTGS2 P35354 5/20 0.43
CXCR1 P25024 4/20 0.43
CXCR2 P25025 4/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
CHRM1 P11229 1/20 0.40
PDE4A P27815 1/20 0.40
PTGS1 P23219 3/20 0.40
LMNA P02545 2/20 0.40
CYP2C9 P11712 2/20 0.40
AKR1C3 P42330 2/20 0.40
ALB P02768 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX5 P09917 1/20 0.40
RARB P10826 1/20 0.40
ADRB3 P13945 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454165 0.80 CXCR1 (0.49) ALDH1A1PTGS2CXCR1CXCR2CA12
SCHEMBL10154287 0.79 KMT2A (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL18249745 0.78 TMEM97 (0.52) ALDH1A1PTGS2CA1CA2CHRM1
SCHEMBL5321195 0.78 TAAR1 (0.52) ALDH1A1CA12CA1CA2CA4
SCHEMBL6457789 0.78 RECQL (0.58) ALDH1A1PTGS2CXCR1CXCR2CA12
SCHEMBL1275321 0.78 RECQL (0.58) ALDH1A1CA12CA1CA2CA9
SCHEMBL10154041 0.78 TAAR1 (0.52) ALDH1A1CA12CA1CA2CA4
SCHEMBL6793104 0.77 IDO1 (0.59) ALDH1A1CA12CA1CA2CA9
SCHEMBL6454513 0.77 MMP8 (0.45) ALDH1A1PTGS2CXCR1CXCR2CA12
SCHEMBL6458675 0.76 ALDH1A1 (0.49) ALDH1A1PTGS2CXCR1CXCR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1606248-A2 SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dompé S.P.A. (IT) 2005-12-21 EP disclosed
WO-2004080951-A2 SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DOMPE S.P.A. (IT) 2004-09-23 WO disclosed