Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP12 | P39900 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459533 | 0.79 | ALDH1A1 (0.67) | ALDH1A1LMNANPC1HPGDRAB9A | |
| SCHEMBL6460525 | 0.79 | ALDH1A1 (0.49) | MMP8MMP12MMP13ALDH1A1LMNA | |
| SCHEMBL688365 | 0.77 | PTGS2 (0.44) | PTGS2ALDH1A1LMNANPC1HPGD | |
| SCHEMBL6460105 | 0.77 | ALDH1A1 (0.47) | PTGS2ALDH1A1LMNAKDM4ECA12 | |
| SCHEMBL6461315 | 0.76 | MMP8 (0.44) | MMP8MMP12MMP13PTGS2ALDH1A1 | |
| SCHEMBL688439 | 0.74 | MEN1 (0.43) | PTGS2ALDH1A1LMNANPC1HPGD | |
| SCHEMBL10072758 | 0.74 | MEN1 (0.43) | PTGS2ALDH1A1LMNANPC1HPGD | |
| SCHEMBL8603942 | 0.74 | NR3C1 (0.44) | PTGS2LMNASLC6A4CXCR1CXCR2 | |
| SCHEMBL6454165 | 0.72 | CXCR1 (0.49) | MMP8MMP12MMP13PTGS2ALDH1A1 | |
| SCHEMBL16701716 | 0.71 | MMP8 (0.49) | MMP8MMP12MMP13ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080951-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2004-09-23 | — | — | WO | disclosed |