Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142862 | 0.83 | IDO1 (0.47) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1044636 | 0.76 | IDO1 (0.47) | ACMSDHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL9777674 | 0.76 | IDO1 (0.47) | ACMSDHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL1193247 | 0.75 | TRPM4 (0.41) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1322927 | 0.75 | TRPM4 (0.41) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17707246 | 0.74 | GLA (0.44) | HPGDKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL4802146 | 0.74 | KDM4E (0.44) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10501308 | 0.73 | BACE1 (0.40) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22981765 | 0.72 | TRPM4 (0.39) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11764391 | 0.72 | TRPM4 (0.39) | HPGDKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107669664-B | Compositions for respiratory delivery of active agents and related methods and systems | 珍珠治疗公司 | 2020-07-10 | — | — | CN | claimed |
| EP-0538193-B1 | Condensed cycloaliphatir-amidino-hydrazon salts as S-adenosylmethionin decarboxylase inhibitors | CIBA GEIGY AG (CH) | 1996-12-04 | — | — | EP | claimed |
| CN-116710104-A | Pharmaceutical compositions deliverable by metered dose inhaler | 江苏恒瑞医药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-107412212-B | Pulmonary delivery of long-acting muscarinic antagonists and long-acting beta2Compositions of adrenergic receptor agonists and related methods and systems | 珍珠治疗公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-107669664-B | Compositions for respiratory delivery of active agents and related methods and systems | 珍珠治疗公司 | 2020-07-10 | — | — | CN | disclosed |
| US-8778948-B2 | Substituted phenylpiperazinyl aralkylalcohol derivatives, pharmaceutical compositions containing such derivatives and uses thereof | NHWA Pharma, Corporation (CN) | 2014-07-15 | — | — | US | disclosed |
| CN-103687483-A | Compositions, methods and systems for respiratory delivery of two or more active agents | PEARL THERAPEUTICS INC | 2014-03-26 | — | — | CN | disclosed |
| CN-102753152-A | Respiratory Delivery of Active Agents | PEARL THERAPEUTICS INC | 2012-10-24 | — | — | CN | disclosed |
| CN-102596176-A | Compositions for respiratory delivery of active agents and related methods and systems | PEARL THERAPEUTICS INC | 2012-07-18 | — | — | CN | disclosed |
| CN-102458364-A | Pulmonary delivery of long-acting muscarinic antagonists and long-acting beta2Compositions of adrenergic receptor agonists and related methods and systems | PEARL THERAPEUTICS INC | 2012-05-16 | — | — | CN | disclosed |
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | NHWA PHARMA. CORPORATION (CN) | 2011-12-15 | — | — | US | disclosed |
| WO-1997040029-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | NOVARTIS AG (CH) | 1997-10-30 | — | — | WO | disclosed |
| WO-1997027199-A1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |
| US-5639911-A | Hydrazones | CIBA-GEIGY CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1997016452-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-05-09 | — | — | WO | disclosed |
| WO-1997002266-A1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 1997-01-23 | — | — | WO | disclosed |
| WO-1996031510-A1 | PYRAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 1996-10-10 | — | — | WO | disclosed |
| CN-1128263-A | Pyrrolopyrimidine derivatives having pharmacological activity | CIBA GEIGY AG (CH) | 1996-08-07 | — | — | CN | disclosed |
| US-5461076-A | Inhibitors of S-adenosylmethionine decarboxylase; antitumor agents | NOVARTIS CORPORATION | 1995-10-24 | — | — | US | disclosed |
| US-5395855-A | Antitumor agents | CIBA-GEIGY CORPORATION (US) | 1995-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | HTR2A, HTR2C, HTR5A | ACMSD 2659/4885HPGD 1830/4885KDM4E 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.