Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 5/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451910 | 1.00 | GRM2 (0.33) | GRM2GAAMAPTRAB9ACRHR1 | |
| SCHEMBL6451906 | 1.00 | GRM2 (0.33) | GRM2GAAMAPTRAB9ACRHR1 | |
| SCHEMBL6461170 | 1.00 | GRM2 (0.33) | GRM2GAAMAPTRAB9ACRHR1 | |
| SCHEMBL6452248 | 0.99 | RAB9A (0.32) | GRM2GAAMAPTRAB9ACRHR1 | |
| SCHEMBL6452246 | 0.99 | RAB9A (0.32) | GRM2GAAMAPTRAB9ACRHR1 | |
| SCHEMBL6460297 | 0.96 | RAB9A (0.33) | RAB9ACRHR1DRD2CNR1CNR2 | |
| SCHEMBL6460302 | 0.96 | RAB9A (0.33) | RAB9ACRHR1DRD2CNR1CNR2 | |
| SCHEMBL6464218 | 0.92 | DRD2 (0.33) | CRHR1DRD2CCNB2CDK1CCNB1 | |
| SCHEMBL6464222 | 0.92 | DRD2 (0.33) | CRHR1DRD2CCNB2CDK1CCNB1 | |
| SCHEMBL6458881 | 0.89 | PTGS1 (0.34) | GRM2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |