Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464222 | 1.00 | DRD2 (0.33) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6460302 | 0.94 | RAB9A (0.33) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6460297 | 0.94 | RAB9A (0.33) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452248 | 0.93 | RAB9A (0.32) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452246 | 0.93 | RAB9A (0.32) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6461170 | 0.92 | GRM2 (0.33) | DRD2CRHR1CCR2CCNB2CDK1 | |
| SCHEMBL6451910 | 0.92 | GRM2 (0.33) | DRD2CRHR1CCR2CCNB2CDK1 | |
| SCHEMBL6451906 | 0.92 | GRM2 (0.33) | DRD2CRHR1CCR2CCNB2CDK1 | |
| SCHEMBL6461165 | 0.92 | GRM2 (0.33) | DRD2CRHR1CCR2CCNB2CDK1 | |
| SCHEMBL6464093 | 0.91 | SLC6A2 (0.35) | DRD2CRHR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |