Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CCKBR | P32239 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 3/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6021347 | 0.86 | TACR1 (0.63) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6020622 | 0.85 | TACR1 (0.56) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6020035 | 0.84 | MMP9 (0.53) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6020901 | 0.83 | CTSL (0.68) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6019319 | 0.83 | CTSL (0.54) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6019347 | 0.83 | CCKBR (0.56) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6021416 | 0.83 | KMT2A (0.59) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6021893 | 0.83 | TACR1 (0.53) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6019870 | 0.83 | MEN1 (0.57) | MMP9MMP8MMP14CTSLTACR1 | |
| SCHEMBL6019670 | 0.83 | MMP9 (0.52) | MMP9MMP8MMP14CTSLTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |