Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564623 | 0.92 | PTGDR2 (0.54) | AGTR1PTGDR2PTGDRHTR6ACLY | |
| SCHEMBL3562959 | 0.87 | AGTR1 (0.57) | AGTR1PTGDR2PTGDRHTR6ACLY | |
| SCHEMBL6423753 | 0.86 | ACLY (0.59) | AGTR1PTGDR2PTGDRLMNAHTR6 | |
| SCHEMBL6421393 | 0.84 | ACLY (0.53) | AGTR1PTGDR2PTGDRHTR6ACLY | |
| SCHEMBL29273775 | 0.84 | AGTR1 (0.50) | AGTR1PTGDR2PTGDRLMNAHTR6 | |
| SCHEMBL30641514 | 0.84 | AGTR1 (0.50) | AGTR1PTGDR2PTGDRLMNAHTR6 | |
| SCHEMBL6425246 | 0.83 | PTGDR2 (0.67) | AGTR1PTGDR2PTGDRLMNAHTR6 | |
| SCHEMBL3558278 | 0.80 | PTGDR2 (0.68) | PTGDR2PTGDRLMNAHTR6ACLY | |
| SCHEMBL29839951 | 0.78 | AGTR1 (0.62) | AGTR1PTGDR2HTR6ACLYALDH3A1 | |
| SCHEMBL946467 | 0.78 | HTR6 (0.61) | AGTR1PTGDR2PTGDRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |