Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464611 | 0.77 | TSHR (0.39) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| SCHEMBL16210936 | 0.73 | RIPK1 (0.43) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| SCHEMBL29732720 | 0.73 | RIPK1 (0.43) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL57497 | 0.73 | ALDH1A1 (0.48) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL56184 | 0.73 | ALDH1A1 (0.48) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27730332 | 0.73 | ALDH1A1 (0.48) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| SCHEMBL16015530 | 0.71 | AOC3 (0.55) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 | |
| SCHEMBL1471159 | 0.71 | SLC6A4 (0.45) | SLC6A4SLC6A3RIPK1ALDH1A1AOC3 | |
| SCHEMBL12574668 | 0.71 | SLC6A4 (0.45) | SLC6A4SLC6A3RIPK1ALDH1A1AOC3 | |
| SCHEMBL2364517 | 0.71 | AOC3 (0.55) | SLC6A4SLC6A2SLC6A3RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |