Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462736 | 0.77 | SLC6A4 (0.40) | SLC6A4RIPK1MEN1KMT2AHBB | |
| SCHEMBL575475 | 0.71 | MPO (0.40) | TSHRTDP1ALDH1A1DPP4TAAR1 | |
| SCHEMBL30923543 | 0.71 | SLC6A4 (0.45) | TSHRSLC6A4RIPK1MEN1KMT2A | |
| SCHEMBL27300404 | 0.71 | TSHR (0.42) | TSHRSLC6A4RIPK1SLC6A3TDP1 | |
| SCHEMBL27270815 | 0.70 | DPP4 (0.46) | TSHRSLC6A4ALDH1A1AOC3KDM4E | |
| SCHEMBL10956757 | 0.69 | IDO1 (0.41) | TSHRSLC6A4MEN1KMT2ASLC6A3 | |
| SCHEMBL576245 | 0.68 | POLB (0.37) | TSHRMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1575568 | 0.65 | TSHR (0.52) | TSHRTDP1HRH1KDM4ELMNA | |
| SCHEMBL28825921 | 0.65 | ATM (0.49) | SLC6A4RIPK1MEN1KMT2ALMNA | |
| SCHEMBL6459735 | 0.65 | ALDH1A1 (0.38) | TSHRSLC6A4RIPK1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |