SCHEMBL6463039

SCHEMBL6463039

COc1ccc(S(=O)(=O)NC(=O)Nc2ccc(C(C)(C)c3ccc(NC(=O)NS(=O)(=O)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.60
HRH3 Q9Y5N1 1/20 0.55
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA9 Q16790 3/20 0.55
POLB P06746 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
KCNA1 Q09470 1/20 0.54
KCNAB1 Q14722 1/20 0.54
IDO1 P14902 1/20 0.52
LMNA P02545 2/20 0.52
TP53 P04637 1/20 0.51
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA5A P35218 1/20 0.51
CA7 P43166 1/20 0.51
CA13 Q8N1Q1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9487208 0.88 HRH3 (0.61) HSD17B10HRH3CA12CA1CA2
SCHEMBL6467685 0.86 HSD17B10 (0.61) HSD17B10HRH3CA12CA1CA2
SCHEMBL5187356 0.85 CA12 (0.70) HSD17B10HRH3CA12CA1CA2
SCHEMBL6468377 0.85 CA12 (0.70) CA12CA1CA2CA9RAB9A
SCHEMBL9526067 0.84 POLB (0.76) HSD17B10HRH3CA12CA1CA2
SCHEMBL9526174 0.84 PPIA (0.64) HSD17B10HRH3CA12CA1CA2
SCHEMBL8621686 0.83 LMNA (0.62) HSD17B10HRH3CA12CA1CA2
SCHEMBL7777663 0.83 LMNA (0.71) HSD17B10HRH3CA12CA1CA2
SCHEMBL8662949 0.83 HRH3 (0.72) HSD17B10HRH3CA12CA1CA2
SCHEMBL6467353 0.83 SAE1 (0.71) HSD17B10HRH3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed