SCHEMBL7777663

SCHEMBL7777663

COc1ccc(S(=O)(=O)NC(=O)Nc2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
CYP2C9 P11712 1/20 0.62
HRH3 Q9Y5N1 7/20 0.58
HSD17B10 Q99714 1/20 0.58
KCNH2 Q12809 1/20 0.57
EGFR P00533 1/20 0.57
ERBB2 P04626 1/20 0.57
POLB P06746 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
ALDH1A1 P00352 1/20 0.55
GAA P10253 1/20 0.55
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621686 0.94 LMNA (0.62) LMNACYP2C9HRH3HSD17B10EGFR
SCHEMBL6465069 0.90 CYP19A1 (0.64) LMNAHRH3HSD17B10POLBCA12
SCHEMBL6467685 0.88 HSD17B10 (0.61) LMNAHRH3HSD17B10POLBCA12
SCHEMBL5187356 0.87 CA12 (0.70) LMNAHRH3HSD17B10EGFRPOLB
SCHEMBL7774810 0.87 HSD17B10 (0.67) LMNAHSD17B10POLBNPC1RAB9A
SCHEMBL8659346 0.87 HSD17B10 (0.67) LMNAHSD17B10POLBNPC1RAB9A
SCHEMBL12010877 0.86 PGR (0.70) LMNANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL9526067 0.86 POLB (0.76) CYP2C9HRH3HSD17B10EGFRERBB2
SCHEMBL9526174 0.86 PPIA (0.64) HRH3HSD17B10EGFRERBB2POLB
SCHEMBL6466300 0.85 KCNA1 (0.55) LMNAHRH3HSD17B10POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-0832757-B1 REVERSIBLE THERMAL RECORDING MEDIUM OJI PAPER CO (JP) 2001-08-22 EP disclosed
US-5928988-A CONTAINING SULFONYLUREA COLOR DEVELOPER OJI PAPER CO., LTD. (JP) 1999-07-27 US disclosed
US-5851951-A Heat sensitive recording material OJI PAPER CO., LTD. (JP) 1998-12-22 US disclosed
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0738610-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-17 EP disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
EP-0615859-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed