Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LDLR | P01130 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467112 | 0.84 | CTSK (0.47) | CTSSFAAH | |
| SCHEMBL6463419 | 0.82 | CTSS (0.48) | CTSSFAAHRAB9AMEN1KMT2A | |
| SCHEMBL6468629 | 0.82 | CTSS (0.48) | CTSSFAAHRAB9AMEN1KMT2A | |
| SCHEMBL6465141 | 0.82 | CTSS (0.48) | CTSSFAAHRAB9AMEN1KMT2A | |
| SCHEMBL6464884 | 0.81 | CTSS (0.49) | CTSSFAAHRAB9AMEN1KMT2A | |
| SCHEMBL6063879 | 0.80 | CTSS (0.49) | CTSSFAAHELANE | |
| SCHEMBL13522382 | 0.77 | CTSS (0.49) | CTSSSOAT1HPGDNPC1ALDH1A1 | |
| SCHEMBL6467311 | 0.76 | FAAH (0.44) | CTSSSOAT1FAAHHPGDNPC1 | |
| SCHEMBL12196269 | 0.76 | CTSS (0.69) | CTSSELANE | |
| SCHEMBL27682961 | 0.76 | CTSS (0.54) | CTSSFAAHELANENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |