SCHEMBL6463246

SCHEMBL6463246

Cc1cc(O)c(C)c2c1O[C@@](C)(CO)CC2

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 17/20 0.58
AKT1 P31749 2/20 0.42
PDPK1 O15530 1/20 0.42
PHLPP1 O60346 1/20 0.42
ILK Q13418 1/20 0.42
NR1I2 O75469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028033 1.00 ALOX5 (0.58) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL6027939 1.00 ALOX5 (0.58) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL8600009 0.89 ALOX5 (0.62) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL20819450 0.84 ALOX5 (0.44) ALOX5AKT1NR1I2
SCHEMBL20819449 0.84 ALOX5 (0.44) ALOX5AKT1NR1I2
SCHEMBL8746297 0.82 ALOX5 (0.56) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL8747773 0.82 ALOX5 (0.56) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL2484255 0.81 ALOX5 (0.48) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL4643458 0.81 ALOX5 (0.66) ALOX5NR1I2
Bromide SCHEMBL8599204 0.81 ALOX5 (0.56) ALOX5AKT1PDPK1PHLPP1ILK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124687-A1 Process for synthesizing d-tocotrienols COULADOUROS ELIAS A (GR) 2005-06-09 US disclosed
WO-2005035490-A2 PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS YASOO HEALTH, INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124687-A1 Process for synthesizing d-tocotrienols UGT8, DDOST, GGPS1 ALOX5 219/4885AKT1 3679/4885PDPK1 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.