SCHEMBL2484255

SCHEMBL2484255

Cc1cc(O)c(C)c2c1OC(C)(C)CC2

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 11/20 0.48
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
CCR5 P51681 1/20 0.38
PDE4D Q08499 1/20 0.37
MALT1 Q9UDY8 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
AKT1 P31749 2/20 0.35
PDPK1 O15530 1/20 0.35
PHLPP1 O60346 1/20 0.35
ILK Q13418 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14037240 0.84 LMNA (0.37) ALOX5PTGS1PTGS2CYP1A2CYP3A4
SCHEMBL14283908 0.83 ALOX5 (0.41) ALOX5PTGS1PTGS2CCR5PDE4D
SCHEMBL14283912 0.83 PDE4D (0.38) ALOX5CCR5PDE4DMALT1LMNA
SCHEMBL4468225 0.82 ALOX5 (0.47) ALOX5PTGS1PTGS2CYP1A2CYP3A4
SCHEMBL6027939 0.81 ALOX5 (0.58) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL6028033 0.81 ALOX5 (0.58) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL6463246 0.81 ALOX5 (0.58) ALOX5AKT1PDPK1PHLPP1ILK
SCHEMBL5775188 0.81 CYP1A2 (0.36) ALOX5PTGS1PTGS2CYP1A2CYP3A4
SCHEMBL20822182 0.81 ALOX5 (0.44) ALOX5PTGS1PTGS2CYP1A2CYP3A4
SCHEMBL6027877 0.80 ALOX5 (0.47) ALOX5PTGS1PTGS2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043085-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2025-02-06 US claimed
EP-4448638-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2024-10-23 EP claimed
CN-118401596-A Stabilization of polyisobutene 巴斯夫欧洲公司 2024-07-26 CN claimed
WO-2023110570-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2023-06-22 WO claimed
US-20160324823-A1 TREATMENT OF MITOCHONDRIAL DISEASES BIOELECTRON TECHNOLOGY CORPORATION 2016-11-10 US claimed
US-20130267538-A1 TREATMENT OF MITOCHONDRIAL DISEASES GALILEO PHARMACEUTICALS INC. 2013-10-10 US claimed
US-20070129564-A1 Method for the production of (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-06-07 US claimed
EP-1727780-A1 PROCESS FOR PREPARING (METH)ACRYLIC ESTERS. BASF AKTIENGESELLSCHAFT (DE) 2006-12-06 EP claimed
WO-2005082828-A1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2005-09-09 WO claimed
WO-2005032544-A1 TREATMENT OF MITOCHONDRIAL DISEASES GALILEO PHARMACEUTICALS, INC. (US) 2005-04-14 WO claimed
US-20050065099-A1 Alzheimer's disease; Parkinson's disease; brain disorders; antiepileptic agents; amyotrophic lateral sclerosis; vision defects EDISON PHARMACEUTICALS, INC. 2005-03-24 US claimed
US-20250043085-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2025-02-06 US disclosed
EP-4448638-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2024-10-23 EP disclosed
CN-118401596-A Stabilization of polyisobutene 巴斯夫欧洲公司 2024-07-26 CN disclosed
WO-2023110570-A1 STABILISATION OF POLYISOBUTENE BASF SE (DE) 2023-06-22 WO disclosed
WO-2005032544-A1 TREATMENT OF MITOCHONDRIAL DISEASES GALILEO PHARMACEUTICALS, INC. (US) 2005-04-14 WO disclosed
US-20050065099-A1 Alzheimer's disease; Parkinson's disease; brain disorders; antiepileptic agents; amyotrophic lateral sclerosis; vision defects EDISON PHARMACEUTICALS, INC. 2005-03-24 US disclosed
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed
US-6465548-B1 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129564-A1 Method for the production of (meth)acrylic acid esters MMAB, ACR, MCCC2 ALOX5 378/4885PTGS1 861/4885PTGS2 1000/4885
US-20050065099-A1 Alzheimer's disease; Parkinson's disease; brain disorders; antiepileptic agents; amyotrophic lateral sclerosis; vision defects CLN6, LDHA, NLN ALOX5 1992/4885PTGS1 3200/4885PTGS2 3398/4885
US-20160324823-A1 TREATMENT OF MITOCHONDRIAL DISEASES NLN, FH, MFN2 ALOX5 1604/4885PTGS1 2790/4885PTGS2 2651/4885
US-20130267538-A1 TREATMENT OF MITOCHONDRIAL DISEASES NLN, FH, MFN2 ALOX5 1604/4885PTGS1 2790/4885PTGS2 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.