Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158149 | 0.82 | HPGD (0.51) | KMT2AMEN1CDK2CCNA2FLT3 | |
| SCHEMBL954249 | 0.82 | ATR (0.54) | KMT2ACDK2CCNA2FLT3CCNA1 | |
| SCHEMBL5265834 | 0.81 | SIRT1 (0.53) | KMT2AMEN1POLBADORA3RAB9A | |
| SCHEMBL957616 | 0.81 | CHRNB2 (0.53) | KMT2ATDP1CDK2CCNA2FLT3 | |
| SCHEMBL13596392 | 0.80 | HDAC1 (0.53) | RAB9ANPC1 | |
| SCHEMBL13816814 | 0.80 | FLT3 (0.49) | KMT2AMEN1CDK2CCNA2FLT3 | |
| SCHEMBL672416 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1CDK2CCNA2FLT3 | |
| SCHEMBL953645 | 0.78 | MAPT (0.58) | KMT2AMEN1TDP1CDK2CCNA2 | |
| SCHEMBL5267186 | 0.78 | NAPRT (0.51) | KMT2AMEN1CDK2CCNA2FLT3 | |
| SCHEMBL26784592 | 0.78 | BCL2 (0.49) | KMT2AMEN1TDP1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | claimed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | claimed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | claimed |
| JP-4648324-B2 | — | — | 2011-03-09 | — | — | JP | claimed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | claimed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | claimed |
| JP-2006528946-A | — | — | 2006-12-28 | — | — | JP | claimed |
| EP-1628962-A1 | IODOPYRAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2006-03-01 | — | — | EP | claimed |
| WO-2004103975-A1 | IODOPYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | claimed |
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |
| US-9051278-B2 | 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators | ASTEX THERAPEUTICS, LTD. (GB) | 2015-06-09 | — | — | US | disclosed |
| EP-2256106-B1 | 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators | ASTEX THERAPEUTICS LTD (GB) | 2015-05-06 | — | — | EP | disclosed |
| US-20140371213-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASE AND GLYCOGEN SYNTHASE KINASE-3 MODULATORS | ASTEX THERAPEUTICS, LTD. (GB) | 2014-12-18 | — | — | US | disclosed |
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-1628962-A1 | IODOPYRAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| EP-1599460-A2 | OXATHIIN CARBOXAMIDE | Bayer CropScience Aktiengesellschaft (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
| WO-2004103975-A1 | IODOPYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004103975-A1 | IODOPYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004072023-A2 | OXATHIIN CARBOXAMIDE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | KMT2A 1545/4885MEN1 522/4885TDP1 2029/4885 |
| US-20140371213-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASE AND GLYCOGEN SYNTHASE KINASE-3 MODULATORS | CDK1, CDK3, CDK13 | KMT2A 1833/4885MEN1 1465/4885TDP1 2533/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | KMT2A 1930/4885MEN1 353/4885TDP1 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.