Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047033 | 0.86 | FAAH (0.41) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6462832 | 0.82 | DAGLA (0.43) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL7043208 | 0.80 | FAAH (0.41) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL7045310 | 0.78 | FAAH (0.38) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6467434 | 0.76 | HDAC6 (0.40) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6478317 | 0.75 | FAAH (0.38) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6461887 | 0.75 | DRD2 (0.41) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL7045344 | 0.75 | FAAH (0.41) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6463821 | 0.72 | DAGLA (0.40) | FAAHDAGLACES1P2RY14MAPT | |
| SCHEMBL6466177 | 0.72 | DAGLA (0.44) | FAAHDAGLACES1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |