SCHEMBL6463554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5554155	0.91	PTGS2 (0.66)	PTGS2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL5559469	0.91	PTGS2 (0.58)	PTGS2AKR1C3AKR1C2PTGS1PPARG
	SCHEMBL5800579	0.91	PTGS2 (0.68)	PTGS2AKR1C3AKR1C2PTGS1HRH4
	SCHEMBL5554099	0.89	AKR1C3 (0.83)	PTGS2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL5554744	0.89	PTGS2 (0.80)	PTGS2AKR1C3AKR1C2PTGS1HRH4
	SCHEMBL5800455	0.89	PTGS2 (0.69)	PTGS2AKR1C3AKR1C2PTGS1HRH4
	SCHEMBL5797917	0.89	PTGS2 (0.86)	PTGS2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL6424723	0.89	PTGS2 (0.78)	PTGS2AKR1C3AKR1C2NPSR1PTGS1
	SCHEMBL5553987	0.88	PTGS2 (0.67)	PTGS2AKR1C3AKR1C2LMNACYP1A2
	SCHEMBL5559102	0.88	PTGS2 (0.67)	PTGS2AKR1C3AKR1C2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.