Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 6/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 5/20 | 0.34 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463139 | 1.00 | AR (0.53) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL6462161 | 0.85 | AR (0.74) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6467016 | 0.81 | AR (0.48) | ARPGRNR3C2ADORA3SLC6A2 | |
| SCHEMBL6464468 | 0.79 | AR (0.51) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL13770469 | 0.77 | PDK1 (0.48) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL2834009 | 0.77 | AR (0.71) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL13216966 | 0.77 | AR (0.71) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL14216488 | 0.76 | PDK1 (0.43) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL14216486 | 0.76 | PDK1 (0.43) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL13796867 | 0.74 | PDK1 (0.43) | ARPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881728-B1 | 14-β, 17-α-hydroxymethylandrostane derivatives as androgens | AKZO NOBEL N.V. (NL) | 2005-04-19 | — | — | US | disclosed |
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |