Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463683 | 1.00 | KDM1A (0.34) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL6457090 | 0.84 | KDM1A (0.34) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL6457093 | 0.84 | KDM1A (0.34) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL6455522 | 0.84 | MAP1LC3B (0.35) | KDM1AHDAC2HTR2CHTR2B | |
| SCHEMBL6451317 | 0.84 | HTR3A (0.38) | — | |
| SCHEMBL6451314 | 0.84 | HTR3A (0.38) | — | |
| SCHEMBL6455518 | 0.84 | MAP1LC3B (0.35) | KDM1AHDAC2HTR2CHTR2B | |
| SCHEMBL6665053 | 0.83 | HDAC2 (0.41) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL6451193 | 0.80 | KDM1A (0.39) | KDM1AMAOBHTR2C | |
| SCHEMBL6451194 | 0.80 | KDM1A (0.39) | KDM1AMAOBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |