Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853901 | 0.89 | HDAC2 (0.43) | HDAC2MAOBESR2HDAC8HDAC6 | |
| SCHEMBL6463683 | 0.83 | KDM1A (0.34) | HDAC2BRD4KDM1AKCNH2MAOB | |
| SCHEMBL6463686 | 0.83 | KDM1A (0.34) | HDAC2BRD4KDM1AKCNH2MAOB | |
| SCHEMBL265495 | 0.82 | KDM1A (0.48) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL14804315 | 0.82 | KDM1A (0.48) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL1506370 | 0.82 | KDM1A (0.42) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL1506333 | 0.82 | KDM1A (0.42) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL1506335 | 0.82 | KDM1A (0.42) | BRD4KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL9252545 | 0.80 | MAP1LC3B (0.40) | HDAC2KDM1AESR2 | |
| SCHEMBL9805549 | 0.80 | DGAT1 (0.39) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237849-A1 | LIQUID CRYSTAL COMPOUNDS AND METHOD FOR PREPARING THE SAME | Dongjin Semichem Co., Ltd., (KR) | 2011-09-29 | — | — | US | disclosed |
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-0893423-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0471287-B1 | Alkoxypropenyl derivatives | HOFFMANN LA ROCHE (CH) | 1995-06-21 | — | — | EP | disclosed |
| US-5288428-A | Liquid crystal compounds having a terminal alkoxy propenyl group | HOFFMANN-LA ROCHE INC. (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0471287-A1 | Alkoxypropenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237849-A1 | LIQUID CRYSTAL COMPOUNDS AND METHOD FOR PREPARING THE SAME | HCK, NLK, VRK1 | HDAC2 3784/4885BRD4 1526/4885KDM1A 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.