SCHEMBL6463716 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NAAA	Q02083	2/20	0.39

▸	CTSK	P43235	1/20	0.39

▸	GRM2	Q14416	5/20	0.35

▸	HRH3	Q9Y5N1	1/20	0.34

▸	PDE2A	O00408	5/20	0.33

▸	KDM1A	O60341	2/20	0.33

▸	EPHX2	P34913	2/20	0.33

▸	HCRTR1	O43613	1/20	0.32

▸	HCRTR2	O43614	1/20	0.32

▸	S1PR1	P21453	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6463710	1.00	NAAA (0.39)	NAAACTSKGRM2HRH3PDE2A
SCHEMBL6457405	0.90	KDM1A (0.32)	NAAACTSKKDM1A
SCHEMBL6457411	0.90	KDM1A (0.32)	NAAACTSKKDM1A
SCHEMBL6451732	0.89	CTSK (0.36)	NAAACTSKGRM2PDE2AKDM1A
SCHEMBL6451727	0.89	CTSK (0.36)	NAAACTSKGRM2PDE2AKDM1A
SCHEMBL6452195	0.89	CTSK (0.35)	NAAACTSKGRM2PDE2AKDM1A
SCHEMBL6452190	0.89	CTSK (0.35)	NAAACTSKGRM2PDE2AKDM1A
SCHEMBL6465196	0.88	KDM1A (0.45)	NAAAKDM1A
SCHEMBL6465199	0.88	KDM1A (0.45)	NAAAKDM1A
SCHEMBL10013944	0.88	ESR2 (0.41)	NAAACTSKGRM2PDE2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6913797-B1	Decahydronaphthalene derivative	DAINIPPON INK AND CHEMICALS, INC. (JP)	2005-07-05	—	—	US	disclosed
EP-1108700-A1	DECAHYDRONAPHTHALENE DERIVATIVE	DAINIPPON INK AND CHEMICALS, INC. (JP)	2001-06-20	—	—	EP	disclosed