SCHEMBL6463953

SCHEMBL6463953

CC(=O)O[SiH](O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825361 0.95 TSHR (0.32) TSHRALDH1A1
SCHEMBL550562 0.77 TSHR (0.31) TSHRALDH1A1
SCHEMBL203518 0.76 ALDH1A1 (0.44) TSHRALDH1A1
SCHEMBL20680488 0.74 ALDH1A1 (0.41) TSHRALDH1A1
Fluoromethane SCHEMBL28191693 0.71 ALDH1A1 (0.39) TSHRALDH1A1
Ethylene SCHEMBL27488666 0.71 ALDH1A1 (0.39) TSHRALDH1A1
Trimethylammonium SCHEMBL5391194 0.69 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL9007767 0.69 ALDH1A1 (0.44) TSHRALDH1A1
Tetramethylammonium Ion SCHEMBL5398916 0.69 ALDH1A1 (0.37) TSHRALDH1A1
Dimethylamine SCHEMBL5389239 0.69 ALDH1A1 (0.44) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1572701-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2005-09-14 EP claimed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
EP-1572701-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2005-09-14 EP disclosed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 WO disclosed