Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057259 | 0.88 | MMP12 (0.54) | MMP12MMP13ADAM17 | |
| SCHEMBL4057254 | 0.88 | MMP12 (0.54) | MMP12MMP13ADAM17 | |
| SCHEMBL4053424 | 0.87 | MMP12 (0.57) | MMP12MMP13ADAM17 | |
| SCHEMBL4053430 | 0.87 | MMP12 (0.57) | MMP12MMP13ADAM17 | |
| SCHEMBL4059425 | 0.86 | ADAM17 (0.54) | MMP12MMP13ADAM17 | |
| SCHEMBL4059420 | 0.86 | ADAM17 (0.54) | MMP12MMP13ADAM17 | |
| SCHEMBL4556570 | 0.86 | ADAM17 (0.54) | MMP12MMP13ADAM17 | |
| SCHEMBL4442454 | 0.86 | MMP12 (0.67) | MMP12MMP13ADAM17 | |
| SCHEMBL4057183 | 0.86 | MMP12 (0.52) | MMP12MMP13ADAM17 | |
| SCHEMBL6527878 | 0.86 | MMP12 (0.67) | MMP12MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890915-B2 | Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-05-10 | — | — | US | claimed |