Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049748 | 0.90 | XDH (0.40) | XDHLMNAKMT2ADAGLAFAAH | |
| SCHEMBL6475520 | 0.89 | DAGLA (0.50) | XDHDAGLAFAAHCES1 | |
| SCHEMBL6467552 | 0.82 | DAGLA (0.51) | XDHDAGLAFAAHCES1 | |
| SCHEMBL7046959 | 0.79 | DAGLA (0.45) | XDHDAGLAFAAHCES1 | |
| SCHEMBL6463072 | 0.76 | DAGLA (0.60) | XDHDAGLAFAAHCES1 | |
| SCHEMBL14110447 | 0.75 | KMT2A (0.46) | XDHLMNAKMT2AALDH1A1ALOX12 | |
| SCHEMBL6061790 | 0.75 | BCHE (0.37) | XDHDAGLAFAAHCES1ALDH1A1 | |
| SCHEMBL7045497 | 0.74 | DAGLA (0.46) | XDHDAGLAFAAHCES1 | |
| SCHEMBL6461916 | 0.73 | HSF1 (0.42) | XDHLMNAKMT2ADAGLAFAAH | |
| SCHEMBL7567535 | 0.73 | DAGLA (0.43) | LMNAKMT2ADAGLAFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |