Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 10/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475520 | 0.93 | DAGLA (0.50) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL7045497 | 0.89 | DAGLA (0.46) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL6463072 | 0.88 | DAGLA (0.60) | DAGLAFAAHCES1XDH | |
| SCHEMBL14110405 | 0.86 | FAAH (0.44) | DAGLAFAAHCES1XDH | |
| SCHEMBL7046959 | 0.84 | DAGLA (0.45) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL6464573 | 0.82 | XDH (0.44) | DAGLAFAAHCES1XDH | |
| SCHEMBL6464404 | 0.81 | DAGLA (0.48) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL7049749 | 0.81 | DAGLA (0.50) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL7046458 | 0.81 | DAGLA (0.44) | DAGLAFAAHCES1XDHPPARG | |
| SCHEMBL7049760 | 0.78 | DAGLA (0.54) | DAGLAFAAHCES1XDHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |