Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464726 | 1.00 | KDM1A (0.43) | KDM1APTGS2PTGS1TDP2NAAA | |
| SCHEMBL6452195 | 0.89 | CTSK (0.35) | KDM1ANAAA | |
| SCHEMBL6452190 | 0.89 | CTSK (0.35) | KDM1ANAAA | |
| SCHEMBL6460316 | 0.89 | GRM2 (0.34) | KDM1A | |
| SCHEMBL6460319 | 0.89 | GRM2 (0.34) | KDM1A | |
| SCHEMBL6465199 | 0.88 | KDM1A (0.45) | KDM1APTGS2PTGS1TDP2NAAA | |
| SCHEMBL6465196 | 0.88 | KDM1A (0.45) | KDM1APTGS2PTGS1TDP2NAAA | |
| SCHEMBL6463251 | 0.87 | NOTUM (0.32) | KDM1APTGS2 | |
| SCHEMBL6463255 | 0.87 | NOTUM (0.32) | KDM1APTGS2 | |
| SCHEMBL6459540 | 0.86 | MEN1 (0.33) | KDM1AL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |