Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 11/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523159 | 0.77 | DAGLA (0.56) | DAGLAFAAHCES1XDH | |
| SCHEMBL6465151 | 0.74 | DAGLA (0.51) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6464297 | 0.73 | DAGLA (0.44) | DAGLAFAAHCES1XDHPRSS8 | |
| SCHEMBL6466904 | 0.72 | DAGLA (0.50) | DAGLAFAAHCES1XDHPRSS8 | |
| SCHEMBL6465159 | 0.71 | FAAH (0.44) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6463782 | 0.71 | CTSS (0.43) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6463433 | 0.71 | DAGLA (0.42) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL14378300 | 0.70 | DAGLA (0.54) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6466589 | 0.70 | DAGLA (0.56) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6466909 | 0.70 | DAGLA (0.56) | DAGLAFAAHCES1XDHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |